Original Skunk #1 was originally created by Sacred Seeds on the west coast of the USA during the second half of the 1970s. Bred by crossing an Afghani Indica, Acapulco Gold Mexican Sativa and a Colombian Gold sativa. It was the very first stabilised hybrid to be introduced to the burgeoning Dutch growing scene. It was then commonly called ""sinsemilla"" - grown for potency as seedless marijuana and prevented from becoming fertilised in order to harness all of the plant's energy to be used for resin production and not for seeds.

Its stabilisation resulted in its utilisation as breeding stock for almost all of the Skunk strains currently available as well as for many other strains as well. As such it was seen as the ""gold standard"" for modern, hybrid cannabis. Its dense buds vary from a light green to a golden colour and are liberally packed with THC-carrying resin. Its taste is somewhat sweet with a decidedly strong aroma (hence the name) and it delivers a powerful, cerebral high effect. Due to the very high ratio of buds to larger leaves it is a strain that is very easy to manicure following its harvest and drying.